Copyright 1996, Revised 2003 by Larry Bickford. All Rights Reserved.

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The EyeCare Connection

The EyeCare Reports


PLEASE READ THIS: The information contained herein is not intended as a substitute for medical advice and care from qualified, licensed health care providers. The reader should regularly consult a physician in matters relating to his or her health and particularly with respect to any symptoms that may require diagnosis or medical attention. The information is presented here to educate and inform and to guide you to an understanding of cause, prevention as well as treatment.

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Pinguecula and Pterigium

The callous on the eye

By E. Lawrence Bickford, O.D.

There are two conditions which are often referred to as "the callous on the eye". At first glance, they appear similar, consisting of a raised, often yellowish or yellow-white patch, occasionally with irritated blood vessels, next to the cornea on the "white of the eye".

Pinguecula (ping gwek-u-la)

A very common lesion occurring from damage to the conjunctiva, the thin membrane which lines the sclera ("white of the eye") and the inside of the eyelids. It is often referred to as a "fatty degeneration" of the tissue. The fine, nearly transparent collagen fibers degenerate and are replaced by thicker, yellowish, more durable fibers and sometimes calcium crystals. This causes the elevated, yellow and sometimes glistening whitish area located next to the cornea. Basically, a callous! Often, there are no symptoms and the patient merely complains of the cosmetic concern.

If the area is significantly raised or has a lot of calcium crystals, the conjunctiva becomes further irritated as the eyelid crosses the area. Additionally, dry eye conditions cause even more lid-conjunctiva sensitivity and more symptoms, often resulting in increased yellowing and the appearance of irritated blood vessels.

It is believed that the primary cause of Pinguecula is exposure. We consider exposure to toxic vapors, salt water spray, exposure to the sun (ultraviolet radiation,) and damage to the conjunctiva from insufficient moisture and lubrication (tears) to be the primary causes. Sometimes, the causative factor can be related to computer use, or other intensive near vision activities. We tend to blink less when concentrating on near vision tasks which may contribute to poor tear exchange and dry eye. Pinguecula can appear after only a brief exposure to damaging chemicals or irritation. The tissue damage increases with continued exposure. It might take only a day or two to notice a new Pinguecula but weeks to resolve it.

Treatment

Treatment is to remove the source(s) of irritation and to provide moisture, lubrication and nutritional support so that the conjunctiva can heal. The use of "artificial tears" drops can be helpful. (Products that are preservative-free or that have "disappearing preservatives" are best.)  Nutritional support, such as antioxidants (vitamins C and E and carotenoids) and omega 3 and 6 fats (flaxseed and borage oils, for example) can be effective. Often the condition can be reversed, if not too far advanced. Rapid response and intervention in the process results in less tissue damage and more rapid healing. Long standing Pinguecula are more difficult to resolve and may not respond as well to treatment.  (See "what's new" below.)

Pterigium (terr-idgee-um)

In many ways, Pterigium have similar causes and symptoms to Pinguecula. But unlike the more simple Pinguecula, this condition is sometimes progressive and does involve the cornea, sometimes causing irreparable scarring and permanent damage. If allowed to continue to grow out onto the cornea, it can affect vision. This is seldom the case today where medical care is available as there is treatment to arrest the growth of the Pterigium.

It is believed that there is an underlying pathological cause to Pterigium. Unlike Pinguecula, the lesion develops a blood supply, is attached to the underlying structures, and grows new tissue which invades the adjacent cornea.

Treatment:

Again, prevention is the best method of treatment. Cosmetic concerns and surface irritation are primary patient complaints. Pterigium are less likely than Pinguecula to resolve with simple self treatment and medical intervention is sometimes necessary.

What's New:

New medical treatments for dry eye have recently become available. which include temporary, removable and permanent puncta plugs (to keep whatever tears produced from draining out) and topical and systemic medications, including Restasis. Many "dry eye" drops are now available without potentially irritating preservatives and in longer-lasting gel form.  Restasis, a cyclosporin medicine, was approved for dry eye treatment relating primarily to rheumatoid/autoimmune disorders, in early 2003. Puncta plugs have been around for a while, but the latest generation are "new and improved".